Intracellular growth factors in polycythemia vera and other myeloproliferative disorders.
نویسندگان
چکیده
منابع مشابه
The JAK2V617F mutation in polycythemia vera and other myeloproliferative disorders: one mutation for three diseases?
The discovery of the JAK2V617F mutation has made the diagnosis of polycythemia vera (PV) much easier, but the pathogenesis of PV is still incompletely understood. In particular, it is not yet elucidated how a single mutation can be found in multiple myeloproliferative disorders (MPD) and myelodysplastic syndromes with ring sideroblasts and whether the sole JAK2V617F is sufficient to induce a MP...
متن کاملUpdated and expanded study of polycythemia vera and other myeloproliferative neoplasms in the tri-county area.
INTRODUCTION The results of a 2001-2005 polycythemia vera (PV) investigation in Eastern Pennsylvania revealed a disease cluster plus underreporting and false reporting to the Pennsylvania Cancer Registry (PCR). PURPOSE The objectives of this study were 1) to assess PV reporting to the PCR in 2006-2009, 2) to determine whether a cancer cluster persisted, and 3) to determine whether other myelo...
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This Doctor's MPD Brochure provides basic information for MPD patients and their doctors to better find their way in order to improve proper diagnosis and manage
متن کاملMyeloproliferative Syndrome with Leukemia Preceding Polycythemia Vera : A Case Report
SSOCIATED PROLIFERATION of the various hematologic elements in the marrow, although recognized for some time,2 has recently been the subject of renewed interest.3’8 A close relationship between myelofibrosis and he leukoerythroblastic conditions was demonstrated by Vaughan and HarrisonT in 1939. They suggested that an unknown stimulus acting on the primitive mesenchymal reticulum cell may be re...
متن کاملMyeloproliferative Syndrome with Leukemia Preceding Polycythemia Vera : A Case Report
SSOCIATED PROLIFERATION of the various hematologic elements in the marrow, although recognized for some time,2 has recently been the subject of renewed interest.3’8 A close relationship between myelofibrosis and he leukoerythroblastic conditions was demonstrated by Vaughan and HarrisonT in 1939. They suggested that an unknown stimulus acting on the primitive mesenchymal reticulum cell may be re...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1987
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.84.2.532